McManus became ardent nationalist and a Gaelic League worker in Kiltimagh, County Mayo. Due to her work it is believed up to 7000 people attended a nationalist meeting in the area in 1909.[ She was on the anti-Treaty side of the Civil War in Ireland. She wrote for Penny Pamphlets, published in the Educational Company of Ireland series, and wrote articles for the Irish Independent. Her novel The Professor in Erin (1918) was serialized in the Sinn Féin newspaper, and uses an alternate world scenario to depict "such an Ireland as might have existed had the battle of Kinsale resulted differently, and if Ireland had not been subjected to the plantations that followed that battle".
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